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Article

Heteroplasmic ratio of the A3243G mitochondrial DNA mutation in single pancreatic beta cells.

Diabetologia - 1 Feb 2003

Lynn S, Borthwick G M, Charnley R M, Walker M, Turnbull D M

Abstract excerpt

AIMS/HYPOTHESIS: To examine whether there is a high content of mutated mitochondrial DNA in individual pancreatic beta cells from a patient with the A3243G mitochondrial DNA mutation. METHODS: Tissues were available from a patient with diabetes and the A3243G mutation including pancreatic tissue. We quantified the amount of mutated mitochondrial DNA in tissue homogenates and single pancreatic beta cells using hot...

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Identifiers

PMID: 12627331
DOI: 10.1007/s00125-002-1018-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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