Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms of osteopontin in association with multiple sclerosis in Japanese patients.

Journal of neuroimmunology - 1 Mar 2003

Niino Masaaki, Kikuchi Seiji, Fukazawa Toshiyuki, Yabe Ichiro, Tashiro Kunio

Abstract excerpt

Osteopontin (OPN) exhibits pleiotropic functions and abundant transcripts for OPN are present in brains of patients with multiple sclerosis (MS). The aim of this study was to investigate the role of OPN genes in the pathogenesis of MS. Polymorphisms at the 8090th, 9250th and 9583rd positions in OPN were detected by PCR-RFLP from DNAs of 116 MS Japanese patients and 124 healthy controls. The C/C genotype at the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Chromosomes, Human, Pair 4
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Multiple Sclerosis

Share to Osteopontin

Share to Sialoglycoproteins

Source

Identifiers

PMID: 12620651
DOI: 10.1016/s0165-5728(03)00004-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms of osteopontin in association with multiple sclerosis in Japanese patients.PMID 12620651Read ↗

The impact of osteopontin gene variations on multiple sclerosis development and progression.Semantic proximity Read ↗

The 795CT polymorphism in osteopontin gene is not associated with multiple sclerosis in a Spanish population.Semantic proximity Read ↗

Osteopontin gene haplotypes correlate with multiple sclerosis development and progression.Semantic proximity Read ↗

Osteopontin gene and clinical severity of multiple sclerosis.Semantic proximity Read ↗

Thirteen single-nucleotide polymorphisms in the human osteopontin gene identified by sequencing of the entire gene in Japanese individuals.Semantic proximity Read ↗

Osteopontin polymorphisms and disease course in multiple sclerosis.Semantic proximity Read ↗

Association study of two functional single nucleotide polymorphisms of neuropeptide y gene with multiple sclerosis.Semantic proximity Read ↗

Association Between Osteopontin Gene Polymorphisms and Cerebral Palsy in a Chinese Population.Semantic proximity Read ↗

A single-nucleotide polymorphism of the osteopontin gene may contribute to a susceptibility to Lewy body disease.Semantic proximity Read ↗

The promoter SNP, but not the alternative splicing SNP, is linked to multiple sclerosis among Jordanian patients.Semantic proximity Read ↗

OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population.Semantic proximity Read ↗

Association of Osteopontin gene single nucleotide polymorphism with lupus nephritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.