Article
The degradation of two mitotic cyclins contributes to the timing of cytokinesis.
Current biology : CB - 4 Mar 2003
Echard Arnaud, O'Farrell Patrick H
Abstract excerpt
BACKGROUND: Cytokinesis occurs just as chromosomes complete segregation and reform nuclei. It has been proposed that cyclin/Cdk kinase inhibits cytokinesis until exit from mitosis; however, the timer of cytokinesis has not been experimentally defined. Whereas expression of a stable version of Drosophila cyclin B blocks cytokinesis along with numerous events of mitotic exit, stable cyclin B3 allows cytokinesis...
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