Article
Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity.
Journal of molecular biology - 3 Aug 2001
Carroll M L, Roy-Engel A M, Nguyen S V, Salem A H, Vogel E, Vincent B, Myers J, Ahmad Z, Nguyen L, Sammarco M, Watkins W S, Henke J, Makalowski W, Jorde L B, Deininger P L, Batzer M A
Abstract excerpt
We have utilized computational biology to screen GenBank for the presence of recently integrated Ya5 and Yb8 Alu family members. Our analysis identified 2640 Ya5 Alu family members and 1852 Yb8 Alu family members from the draft sequence of the human genome. We selected a set of 475 of these elements for detailed analyses. Analysis of the DNA sequences from the individual Alu elements revealed a low level of...
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