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Article

The structure and regulation of the human and mouse matrix metalloproteinase-21 gene and protein.

The Biochemical journal - 1 Jun 2003

Marchenko George N, Marchenko Natalia D, Strongin Alex Y

Abstract excerpt

Matrix metalloproteinases (MMPs) play key roles in tissue remodelling under normal development and, especially, in diseases ranging from malignancies to stroke. We cloned and thoroughly characterized the novel human and mouse MMP gene encoding MMP-21. MMP-21 is the last uncharacterized MMP coded by the human genome. Human and mouse MMP-21 is the orthologue of Xenopus laevis X-MMP. The latent proenzyme of MMP-21...

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Source

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Identifiers

PMID: 12617721
DOI: 10.1042/BJ20030174
PMCID: PMC1223413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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