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Article

Association of CCR5Delta32 with reduced risk of childhood but not adult asthma.

Thorax - 1 Mar 2003

Srivastava P, Helms P J, Stewart D, Main M, Russell G

Abstract excerpt

BACKGROUND: A number of potential candidate genes have been implicated in the pathogenesis of asthma. A 32 base pair deletion in the CCR5 gene renders this chemokine receptor non-functioning and has been shown to be associated with a reduced prevalence of asthma in childhood. The mechanism may be related to impairment of pathogen entry into cells and modified host inflammatory response. We sought to determine the...

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Source

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Identifiers

PMID: 12612298
DOI: 10.1136/thorax.58.3.222
PMCID: PMC1746589

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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