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Article

Folding of a highly conserved diverging turn motif from the SH3 domain.

Biophysical journal - 1 Mar 2003

Gnanakaran S, Garcia Angel E

Abstract excerpt

Recent NMR structural characterization studies showed that a seven-residue segment (FKKGERL) from the src SH3 domain adopts the nativelike diverging type II beta-turn in aqueous solution in support of the prediction based on the I-sites library of sequence structural motifs. We study the conformational variability and folding/unfolding thermodynamics of this peptide in explicit solvent using replica-exchange...

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Identifiers

PMID: 12609860
DOI: 10.1016/S0006-3495(03)74966-2
PMCID: PMC1302727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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