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Article

[cag PAI and gastric carcinogenesis-association with p53 gene mutation].

Nihon rinsho. Japanese journal of clinical medicine - 1 Jan 2003

Deguchi Ryuzo, Mine Tetsuya, Miwa Takeshi, Takagi Atsushi

Abstract excerpt

It is widely accepted that carcinogenesis is a multistep process in which regulation of both cell proliferation and apoptosis is disturbed. p53, which is considered the cellular gatekeeper for growth and division, induces apoptosis. Helicobacter pylori(Hp) infection is an accepted risk factor for the development of gastric cancer, but not all infected individuals develop gastric cancer. Because CagA+ Hp induces...

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PMID: 12607313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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