Article
Mechanism of genetic exchange in American trypanosomes.
Nature - 27 Feb 2003
Gaunt Michael W, Yeo Matthew, Frame Iain A, Stothard J Russell, Carrasco Hernan J, Taylor Martin C, Mena Susana Solis, Veazey Paul, Miles Graham A J, Acosta Nidia, de Arias Antonieta Rojas, Miles Michael A
Abstract excerpt
The kinetoplastid Protozoa are responsible for devastating diseases. In the Americas, Trypanosoma cruzi is the agent of Chagas' disease--a widespread disease transmissible from animals to humans (zoonosis)--which is transmitted by exposure to infected faeces of blood-sucking triatomine bugs. The presence of genetic exchange in T. cruzi and in Leishmania is much debated. Here, by producing hybrid clones, we show...
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