Article
Genetic exchange in Trypanosoma brucei: evidence for meiosis from analysis of a cross between drug-resistant transformants.
Molecular and biochemical parasitology - 1 Apr 1994
Gibson W, Bailey M
Abstract excerpt
Genetic exchange in Trypanosoma brucei spp. can occur when two strains are cotransmitted through the tsetse fly vector, but it is non-obligatory and a comparatively rare event. To increase recovery of hybrids, we crossed drug resistant parental strains and selected hybrids by double drug resistan...
Topics
- Alleles
- Animals
- Cloning, Molecular
- Crosses, Genetic
- DNA, Kinetoplast
- DNA, Protozoan
- Drug Resistance
- Electrophoresis, Gel, Pulsed-Field
- Female
- Genes, Protozoan
- Genetic Markers
- Karyotyping
- Male
- Meiosis
- Polymorphism, Restriction Fragment Length
- Polyploidy
- Transformation, Genetic
- Trypanosoma brucei brucei