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Article

Microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid genome diversification.

eLife - 10 May 2022

Matos Gabriel Machado, Lewis Michael D, Talavera-López Carlos, Yeo Matthew, Grisard Edmundo C, Messenger Louisa A, Miles Michael A, Andersson Björn

Abstract excerpt

Protozoa and fungi are known to have extraordinarily diverse mechanisms of genetic exchange. However, the presence and epidemiological relevance of genetic exchange in Trypanosoma cruzi, the agent of Chagas disease, has been controversial and debated for many years. Field studies have identified both predominantly clonal and sexually recombining natural populations. Two of six natural T. cruzi lineages (TcV and...

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Identifiers

PMID: 35535495
DOI: 10.7554/eLife.75237
PMCID: PMC9098224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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