Recent, independent and anthropogenic origins of Trypanosoma cruzi hybrids.

doi:10.1371/journal.pntd.0001363

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Article

Recent, independent and anthropogenic origins of Trypanosoma cruzi hybrids.

PLoS neglected tropical diseases - 1 Oct 2011

Lewis Michael D, Llewellyn Martin S, Yeo Matthew, Acosta Nidia, Gaunt Michael W, Miles Michael A

Abstract excerpt

The single celled eukaryote Trypanosoma cruzi, a parasite transmitted by numerous species of triatomine bug in the Americas, causes Chagas disease in humans. T. cruzi generally reproduces asexually and appears to have a clonal population structure. However, two of the six major circulating genetic lineages, TcV and TcVI, are TcII-TcIII inter-lineage hybrids that are frequently isolated from humans in regions...

Topics

Animals
Chagas Disease
Cluster Analysis
DNA, Protozoan
Evolution, Molecular
Genotype
Haplotypes
Heterozygote
Humans
Microsatellite Repeats
Molecular Sequence Data
Polymorphism, Genetic
Recombination, Genetic
Sequence Analysis, DNA
Trypanosoma cruzi

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PMID: 22022633
DOI: 10.1371/journal.pntd.0001363
PMCID: PMC3191134

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