Article
The determinants of Chagas disease: connecting parasite and host genetics.
Current molecular medicine - 1 Sept 2004
Campbell David A, Westenberger Scott J, Sturm Nancy R
Abstract excerpt
As a consequence of infection by Trypanosoma cruzi, 30% of victims may develop chronic Chagas disease, which presents a spectrum of pathology including cardiomyopathy, megacolon and megaesophagus. The outcome of infection in a particular individual is the result of a set of complex interactions among the host genetic background, environmental and social factors, and the genetic composition of the parasite, all of...
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