The determinants of Chagas disease: connecting parasite and host genetics.

doi:10.2174/1566524043360249

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Article

The determinants of Chagas disease: connecting parasite and host genetics.

Current molecular medicine - 1 Sept 2004

Campbell David A, Westenberger Scott J, Sturm Nancy R

Abstract excerpt

As a consequence of infection by Trypanosoma cruzi, 30% of victims may develop chronic Chagas disease, which presents a spectrum of pathology including cardiomyopathy, megacolon and megaesophagus. The outcome of infection in a particular individual is the result of a set of complex interactions among the host genetic background, environmental and social factors, and the genetic composition of the parasite, all of...

Topics

Animals
Antigens
Biomarkers
Chagas Disease
Disease Models, Animal
Forecasting
Genetic Variation
Host-Parasite Interactions
Humans
Mice
Parasites
Polymorphism, Single Nucleotide
Polyploidy
Trypanosoma cruzi

Source

Open in PubMed

Identifiers

PMID: 15357207
DOI: 10.2174/1566524043360249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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