Article
Human cytomegalovirus glycoprotein N (gpUL73-gN) genomic variants: identification of a novel subgroup, geographical distribution and evidence of positive selective pressure.
The Journal of general virology - 1 Mar 2003
Pignatelli S, Dal Monte P, Rossini G, Chou S, Gojobori T, Hanada K, Guo J J, Rawlinson W, Britt W, Mach M, Landini M P
Abstract excerpt
Human cytomegalvirus (HCMV) ORF UL73 is a polymorphic locus, encoding the viral glycoprotein gpUL73-gN, a component of the gC-II envelope complex. The previously identified gN genomic variants, denoted gN-1, gN-2, gN-3 and gN-4, were further investigated in this work by analysing a large panel of HCMV clinical isolates collected from all over the world (223 samples). Sequencing and phylogenetic analysis confirmed...
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