gpUL73 (gN) genomic variants of human cytomegalovirus isolates are clustered into four distinct genotypes.

doi:10.1099/0022-1317-82-11-2777

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Article

gpUL73 (gN) genomic variants of human cytomegalovirus isolates are clustered into four distinct genotypes.

The Journal of general virology - 1 Nov 2001

Pignatelli S, Dal Monte P, Landini M P

Abstract excerpt

Clinical isolates of human cytomegalovirus (HCMV) show differences in tissue tropism, severity of clinical manifestations and ability to establish persistent or latent infections, characteristics that are thought to be related to genomic variation among strains. This work analysed the genomic variants of a new HCMV polymorphic locus, open reading frame (ORF) UL73. This ORF encodes the envelope glycoprotein gpUL73...

Topics

Amino Acid Sequence
Cytomegalovirus
Cytomegalovirus Infections
Female
Genetic Variation
Genotype
Humans
Infant, Newborn
Molecular Sequence Data
Organ Transplantation
Phylogeny
Pregnancy
Pregnancy Complications, Infectious
Sequence Analysis, DNA
Viral Envelope Proteins

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Identifiers

PMID: 11602789
DOI: 10.1099/0022-1317-82-11-2777

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