Article
Latency-associated human cytomegalovirus glycoprotein N genotypes in monocytes from healthy blood donors.
Transfusion - 1 Oct 2006
Pignatelli Sara, Dal Monte Paola, Rossini Giada, Camozzi Daria, Toscano Vanda, Conte Roberto, Landini Maria Paola
Abstract excerpt
BACKGROUND: The beta-herpesvirus human cytomegalovirus (HCMV) infects a variety of cell types and maintains a lifelong relationship with its host by way of a latent infection in circulating monocytes, myeloid precursor cells, and the hematopoietic progenitor population. Viral strain heterogeneity, shown by gene polymorphisms, has been implicated in the majority of HCMV biologic behaviors. HCMV UL73 encodes the...
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