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Article

Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation.

BMC genomics - 21 May 2018

Krin Evelyne, Pierlé Sebastian Aguilar, Sismeiro Odile, Jagla Bernd, Dillies Marie-Agnès, Varet Hugo, Irazoki Oihane, Campoy Susana, Rouy Zoé, Cruveiller Stéphane, Médigue Claudine, Coppée Jean-Yves, Mazel Didier

Abstract excerpt

BACKGROUND: The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus and in vitro validation. Here, we perform whole transcriptome sequencing from Vibrio cholerae treated with mitomycin C as an SOS inducer to characterize the SOS...

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Identifiers

PMID: 29783948
DOI: 10.1186/s12864-018-4716-8
PMCID: PMC5963079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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