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Article

The conserved Glu-60 residue in Thermoanaerobacter brockii alcohol dehydrogenase is not essential for catalysis.

Protein science : a publication of the Protein Society - 1 Mar 2003

Kleifeld Oded, Shi Shu Ping, Zarivach Raz, Eisenstein Miriam, Sagi Irit

Abstract excerpt

Glu-60 of the zinc-dependent Thermoanaerobacter brockii alcohol dehydrogenase (TbADH) is a strictly conserved residue in all members of the alcohol dehydrogenase (ADH) family. Unlike most other ADHs, the crystal structures of TbADH and its analogs, ADH from Clostridium beijerinckii (CbADH), exhibit a unique zinc coordination environment in which this conserved residue is directly coordinated to the catalytic zinc...

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Identifiers

PMID: 12592017
DOI: 10.1110/ps.0221603
PMCID: PMC2312447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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