Article
A mannosyl transferase required for lipopolysaccharide inner core assembly in Rhizobium leguminosarum. Purification, substrate specificity, and expression in Salmonella waaC mutants.
The Journal of biological chemistry - 2 May 2003
Kanipes Margaret I, Ribeiro Anthony A, Lin Shanhua, Cotter Robert J, Raetz Christian R H
Abstract excerpt
The lipopolysaccharide (LPS) core domain of Gram-negative bacteria plays an important role in outer membrane stability and host interactions. Little is known about the biochemical properties of the glycosyltransferases that assemble the LPS core. We now report the purification and characterization of the Rhizobium leguminosarum mannosyl transferase LpcC, which adds a mannose unit to the inner...
Topics
- Bacterial Proteins
- Escherichia coli
- Glycosylation
- Glycosyltransferases
- Guanosine Diphosphate Mannose
- Lipopolysaccharides
- Mannosyltransferases
- Mutation
- Nuclear Magnetic Resonance, Biomolecular
- O Antigens