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Article

Lipid A biosynthesis in Rhizobium leguminosarum: role of a 2-keto-3-deoxyoctulosonate-activated 4' phosphatase.

Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1995

Price N P, Jeyaretnam B, Carlson R W, Kadrmas J L, Raetz C R, Brozek K A

Abstract excerpt

Lipid A from several strains of the N2-fixing bacterium Rhizobium leguminosarum displays significant structural differences from Escherichia coli lipid A, one of which is the complete absence of phosphate groups. However, the first seven enzymes of E. coli lipid A biosynthesis, leading from UDP-GlcNAc to the phosphorylated intermediate, 2-keto-3-deoxyoctulosonate (Kdo2)-lipid IVA, are present in R. leguminosarum....

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Identifiers

PMID: 7638195
DOI: 10.1073/pnas.92.16.7352
PMCID: PMC41337

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