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Article

A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2

1 Mar 2003

Abstract excerpt

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal-dominant disorder characterized by the age-dependent development of focal arteriovenous malformations and telangiectases. HHT type 2 is caused by loss of function mutations in activin receptor-like kinase 1 (ACVRL1 or ALK1). However, the factors that initiate lesion formation and those that influence disease progression remain unknown. Because...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12588795
DOI: 10.1093/hmg/ddg050

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