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Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome

8 Aug 2016

Abstract excerpt

The repertoire of herpesvirus receptors consists of nonintegrin and integrin molecules. Integrins interact with the conserved glycoproteins gH/gL or gB. This interaction is a conserved biology across the Herpesviridae family, likely directed to promote virus entry and endocytosis. Herpesviruses exploit this interaction to execute a range of critical functions that include (a) relocation of nonintegrin receptors...

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PMID: 27501260
DOI: 10.1146/annurev-virology-110615-035618

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