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Article

Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection.

The Journal of biological chemistry - 15 Jul 2005

Zhang Xuefeng, Wang Jian Feng, Chandran Bala, Persaud Kris, Pytowski Bronislaw, Fingeroth Joyce, Groopman Jerome E

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is the etiologic agent of Kaposi's sarcoma, an endothelial neoplasm. This gamma-herpesvirus encodes for several unique proteins that alter target cell function, including the virion envelope-associated glycoprotein B (gB). Glycoprotein B has an RGD (Arg-Gly-Asp) motif at the extracellular amino terminus region and binds to the...

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Identifiers

PMID: 15878864
DOI: 10.1074/jbc.M411392200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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