Article
Mechanisms by which HPV Induces a Replication Competent Environment in Differentiating Keratinocytes
19 Sept 2017
Abstract excerpt
Human papillomaviruses (HPV) are the causative agents of cervical cancer and are also associated with other genital malignancies, as well as an increasing number of head and neck cancers. HPVs have evolved their life cycle to contend with the different cell states found in the stratified epithelium. Initial infection and viral genome maintenance occurs in the proliferating basal cells of the stratified...
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