Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The mitochondrial DNA A3243G mutation in Werner's syndrome.

Experimental gerontology - 1 Mar 2003

Takeuchi Fujio, Harihara Shinji, Nakamura Kenichi, Takubo Kaiyo, Kanamori Masao, Goto Makoto

Abstract excerpt

OBJECTIVE: The contribution of the A3243G mutation in mitochondria DNA (mtDNA) to diabetes mellitus (DM) in Werner's syndrome (WS) was studied. PATIENTS AND METHOD: DNA samples from peripheral white blood cells (WBCs) originating from 24 Japanese WS patients aged 30-56 were used. For control, 239 subjects aged 15-95 were also used. The mtDNA was amplified using specific primers. After HaeIII digestion, the ratio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Diabetes Mellitus
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to WRN gene

Share to Leukocytes

Share to Mutation

Share to Werner Syndrome

Source

Identifiers

PMID: 12581800
DOI: 10.1016/s0531-5565(02)002090-7

Genes

WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The mitochondrial DNA A3243G mutation in Werner's syndrome.PMID 12581800Read ↗

[Application of next generation sequencing in 3 Waardenburg syndrome].Semantic proximity Read ↗

Molecular and epidemiological studies of Werner syndrome in the Japanese population.Semantic proximity Read ↗

Werner syndrome: a changing pattern of clinical manifestations in Japan (1917~2008).Semantic proximity Read ↗

Molecular analysis of diabetes mellitus-associated A3243G mitochondrial DNA mutation in Taiwanese cases.Semantic proximity Read ↗

The mitochondrial ND1 m.3337G>A mutation associated to multiple mitochondrial DNA deletions in a patient with Wolfram syndrome and cardiomyopathy.Semantic proximity Read ↗

Mitochondrial DNA mutations in diabetes mellitus patients in Chinese Han population.Semantic proximity Read ↗

Recent Trends in WRN Gene Mutation Patterns in Individuals with Werner Syndrome.Semantic proximity Read ↗

Phenotypes and mitochondrial DNA substitutions in families with A3243G mutation.Semantic proximity Read ↗

A novel mutation of the WRN gene in a Chinese patient with Werner syndrome.Semantic proximity Read ↗

Spontaneous event of mitochondrial DNA mutation, A3243G, found in a family of identical twins.Semantic proximity Read ↗

Lipoma and opthalmoplegia in mitochondrial diabetes associated with small heteroplasmy level of 3243 tRNA(Leu(UUR)) mutation.Semantic proximity Read ↗

A3243G mitochondrial DNA mutation in Tunisian diabetic population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.