Article
Angiotensin-converting enzyme genotype predicts valve damage in acute rheumatic fever.
The Journal of heart valve disease - 1 Jan 2003
Atalar Enver, Tokgözoglu S Lale, Alikasifoglu Mehmet, Ovünç Kenan, Aksöyek Serdar, Kes Syrry, Tunçbilek Ergül
Abstract excerpt
BACKGROUND AND AIM OF THE STUDY: The genetic basis for host susceptibility to subsequent valve damage and scarring is not well defined in patients with a history of acute rheumatic fever (ARF). A high angiotensin-converting enzyme (ACE) activity has been demonstrated in valve tissue; hence, the study aim was to determine whether the ACE-DD genotype was a predisposing factor to heart valve damage after ARF attack....
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