Article
Association of angiotensin I-converting enzyme gene insertion/deletion polymorphism with rheumatic heart disease in Indian population and meta-analysis.
Molecular and cellular biochemistry - 1 Oct 2013
Gupta Usha, Mishra Avshesh, Rathore Saurabh S, Agarwal S K, Pande Shantanu, Garg Naveen, Mittal Balraj
Abstract excerpt
Rheumatic heart disease (RHD) is one of the most severe consequences of rheumatic fever. It has been suggested that angiotensin I-converting enzyme (ACE) may be involved in the increased valvular fibrosis and calcification in the pathogenesis of RHD. We conducted a case-control study to look for association of ACE I/D polymorphism with RHD in Indian population. The study incorporated 300 patients (170 males and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.