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Article

TES is a novel focal adhesion protein with a role in cell spreading

6 Feb 2003

Abstract excerpt

Previously, we identified TES as a novel candidate tumour suppressor gene that mapped to human chromosome 7q31.1. In this report we demonstrate that the TES protein is localised at focal adhesions, actin stress fibres and areas of cell-cell contact. TES has three C-terminal LIM domains that appear to be important for focal adhesion targeting. Additionally, the N-terminal region is important for targeting TES to...

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PMID: 12571287
DOI: 10.1242/jcs.00278

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