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Article

High Tau Expression Correlates with Reduced Invasion and Prolonged Survival in Ewing Sarcoma

2025-02-12

Abstract excerpt

The microtubule-associated protein Tau (encoded by the MAPT gene) is linked to a family of neurodegenerative disorders defined as tauopathies, which are characterized by its brain accumulation in neurofibrillary tangles and neuropil threads. Newly described Tau functions comprise DNA protection, chromatin remodeling, p53 regulation and cell fate modulation, suggesting a role of Tau in oncogenesis. Bioinformatic-s...

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Literature Corpus work
aab64cd4-2048-57d6-a736-a244a0c4409c
DOI
10.1101/2025.02.10.635652
Open publication

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High Tau Expression Correlates with Reduced Invasion and Prolonged Survival in Ewing SarcomaDOI 10.1101/2025.02.10.635652
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