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Article

Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains.

Applied and environmental microbiology - 1 Feb 2003

Hwang Yong-Soon, Kim Eung-Soo, Biró Sándor, Choi Cha-Yong

Abstract excerpt

To isolate a gene for stimulating avermectin production, a genomic library of Streptomyces avermitilis ATCC 31267 was constructed in Streptomyces lividans TK21 as the host strain. An 8.0-kb DNA fragment that significantly stimulated actinorhodin and undecylprodigiosin production was isolated. When wild-type S. avermitilis was transformed with the cloned fragment, avermectin production increased approximately...

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Identifiers

PMID: 12571055
DOI: 10.1128/AEM.69.2.1263-1269.2003
PMCID: PMC143579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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