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Article

Human RPE cells express the FGFR2IIIc and FGFR3IIIc splice variants and FGF9 as a potential high affinity ligand.

Experimental eye research - 1 Feb 2003

Alizadeh Mitra, Miyamura Noritake, Handa James T, Hjelmeland Leonard M

Abstract excerpt

The expression of splice variants of FGF receptors, which differ in the third Ig domain, was investigated in retinal pigment epithelium (RPE) cells in vitro and in vivo. This region of the protein determines ligand-binding specificity. Additionally, the expression of potential ligands for these receptors was investigated. Expression of FGF receptor transcript alternative splicing was analyzed by RT-PCR/Southern...

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Source

Identifiers

PMID: 12565813
DOI: 10.1016/s0014-4835(02)00252-x

Genes

RPE
FGF9
FGF4
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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