Article
Effect of the factor VII R353Q missense mutation on plasma apolipoprotein B levels: impact of visceral obesity.
Journal of human genetics - 1 Jan 2003
Berthier Marie-Thérèse, Houde Alain, Bergeron Jean, Prud'homme Denis, Després Jean-Pierre, Vohl Marie-Claude
Abstract excerpt
An atherogenic dyslipidemia, characterized by increased plasma triglyceride and apolipoprotein (apo) B levels, low HDL-cholesterol concentrations and the development of small, dense LDL particles has been associated with the presence of abdominal-visceral obesity. Visceral obesity is also associated with a hypercoagulate state and elevated concentrations of procoagulant factors such as factor VII. Moreover, it is...
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