Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differences in multidrug resistance phenotype and matrix metalloproteinases activity between endothelial cells from normal brain and glioma.

Journal of neurochemistry - 1 Jan 2003

Régina Anthony, Demeule Michel, Bérubé Alexandra, Moumdjian Robert, Berthelet France, Béliveau Richard

Abstract excerpt

Endothelial cells (ECs) are new targets for tumor therapy. In this work, we purified endothelial cells from intracerebral and subcutaneous experimental gliomas as well as from normal brain in order to define some of the phenotypical differences between angiogenic and quiescent brain vasculature. We show that the multidrug resistance genes encoding drug efflux pumps at the brain endothelium are expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple

Share to Endothelium, Vascular

Share to Matrix Metalloproteinases

Share to Neoplasm Transplantation

Share to Rats, Inbred Lew

Share to Subcellular Fractions

Source

Identifiers

PMID: 12558994
DOI: 10.1046/j.1471-4159.2003.01521.x

Genes

MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differences in multidrug resistance phenotype and matrix metalloproteinases activity between endothelial cells from normal brain and glioma.PMID 12558994Read ↗

Characteristics of tumor-associated endothelial cells derived from glioblastoma multiformeSemantic proximity Read ↗

Evidence for a constitutive, verapamil-sensitive, non-P-glycoprotein multidrug resistance phenotype in malignant glioma that is unaltered by radiochemotherapy in vivo.Semantic proximity Read ↗

Functional and phenotypic differences between glioblastoma multiforme-derived and normal human brain endothelial cells.Semantic proximity Read ↗

Expression and functional characterization of ABCG2 in brain endothelial cells and vesselsSemantic proximity Read ↗

Isolation and culture of microvascular endothelial cells from gliomas of different WHO grades.Semantic proximity Read ↗

Tumor cell invasion and angiogenesis in the central nervous system.Semantic proximity Read ↗

Aberrant angiogenic characteristics of human brain arteriovenous malformation endothelial cells.Semantic proximity Read ↗

Overexpression of Multiple Drug Resistance Genes in Endothelial Cells from Patients with Refractory EpilepsySemantic proximity Read ↗

Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosisSemantic proximity Read ↗

Expression and Functional Activity of the ABC-transporter Proteins P-glycoprotein and Multidrug-resistance Protein 1 in Human Brain Tumor Cells and AstrocytesSemantic proximity Read ↗

Matrix Metalloproteinase 1 Is Necessary for the Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Human GliomaSemantic proximity Read ↗

Epirubicin inhibits growth and alters the malignant phenotype of the U‑87 glioma cell line.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.