Article
Aberrant angiogenic characteristics of human brain arteriovenous malformation endothelial cells.
Neurosurgery - 1 Jan 2009
Jabbour Mark N, Elder James B, Samuelson Christian G, Khashabi Shabnam, Hofman Florence M, Giannotta Steven L, Liu Charles Y
Abstract excerpt
OBJECTIVE: To identify and characterize the phenotypic and functional differences of endothelial cells derived from cerebral arteriovenous malformations (AVM), as compared with endothelial cells derived from a normal brain. METHODS: Isolated AVM brain endothelial cells and control brain endothelial cells were evaluated immunohistochemically for expression of the endothelial cell markers von Willebrand factor and...
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