Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific.

The American journal of tropical medicine and hygiene - 1 Jan 2003

Alloueche Ali, Milligan Paul, Conway David J, Pinder Margaret, Bojang Kalifa, Doherty Tom, Tornieporth Nadia, Cohen Joe, Greenwood Brian M

Abstract excerpt

RTS,S/AS02 is a recombinant protein malaria vaccine that contains a large portion of the C-terminal of the circumsporozoite protein (CSP) sequence of the NF54 isolate of Plasmodium falciparum fused to the hepatitis B virus surface antigen. It has been shown to induce significant protection to challenge infection with a homologous parasite strain in American volunteers. In a recently completed trial in semi-immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Protozoan
Share to Hepatitis B Surface Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Malaria, Falciparum

Share to Malaria Vaccines

Share to Plasmodium falciparum

Share to Poisson Distribution

Share to Protozoan Proteins

Share to Vaccines, Synthetic

Source

Identifiers

PMID: 12556156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protective efficacy of the RTS,S/AS02 Plasmodium falciparum malaria vaccine is not strain specific.PMID 12556156Read ↗

RTS,S/AS02A Malaria Vaccine Does Not Induce Parasite CSP T Cell Epitope Selection and Reduces Multiplicity of InfectionSemantic proximity Read ↗

Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine.Semantic proximity Read ↗

Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.Semantic proximity Read ↗

RTS,S/AS01 malaria vaccine mismatch observed among Plasmodium falciparum isolates from southern and central Africa and globally.Semantic proximity Read ↗

Genotypic analysis of RTS,S/AS01E malaria vaccine efficacy against parasite infection as a function of dosage regimen and baseline malaria infection status in children aged 5-17 months in Ghana and Kenya: a longitudinal phase 2b randomised controlled trial.Semantic proximity Read ↗

Variation in the circumsporozoite protein of Plasmodium falciparum: vaccine development implications.Semantic proximity Read ↗

Genotypic analysis of Plasmodium falciparum malaria parasites in a clinical trial of RTS,S vaccination in combination with seasonal malaria chemoprevention.Semantic proximity Read ↗

Genotypic analysis of <i>Plasmodium falciparum</i> malaria parasites in a clinical trial of RTS,S vaccination in combination with seasonal malaria chemopreventionSemantic proximity Read ↗

Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potentialSemantic proximity Read ↗

Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana.Semantic proximity Read ↗

Multi-functional antibodies are induced by the RTS,S malaria vaccine and associated with protection in a phase I/IIa trialSemantic proximity Read ↗

Diverse Antibody Responses to Conserved Structural Motifs in Plasmodium falciparum Circumsporozoite ProteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.