Article
Relationship between functional dopamine D2 and D3 receptors gene polymorphisms and neuroleptic malignant syndrome.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Feb 2003
Mihara Kazuo, Kondo Tsuyoshi, Suzuki Akihito, Yasui-Furukori Norio, Ono Shingo, Sano Akira, Koshiro Kazuko, Otani Koichi, Kaneko Sunao
Abstract excerpt
Our previous study has suggested that the TaqI A polymorphism of dopamine D2 receptor gene (DRD2) is associated with the predisposition to neuroleptic malignant syndrome (NMS). However, the specificity of this polymorphism as a predictor of NMS dose not seem to be sufficient enough. Meanwhile, it has been shown that the non-carriers of Del allele of the -141C Ins/Del polymorphism in the promoter region of DRD2...
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