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Article

Establishment of latrunculin-A resistance in HeLa cells by expression of R183A D184A mutant beta-actin.

Oncogene - 30 Jan 2003

Fujita Masatoshi, Ichinose Sachiyo, Kiyono Tohru, Tsurumi Tatsuya, Omori Akira

Abstract excerpt

Actin plays central roles in cell motility through formation of the actin cytoskeleton. Recently, the very intriguing possibility that actin also contributes to processes in the cell nucleus has been emerging. To dissect its dynamics and functions, several actin-disrupting drugs have been widely and effectively employed. Among them, latrunculin-A has proved particularly useful, supplanting the classical drug...

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PMID: 12555075
DOI: 10.1038/sj.onc.1206173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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