Article
Genetics of sarcoidosis.
Seminars in respiratory and critical care medicine - 1 Feb 2007
Iannuzzi Michael C
Abstract excerpt
Sarcoidosis likely results from an interplay of environmental and genetic factors. Despite a recent large multicenter study, A Case-Control Etiologic Study of Sarcoidosis (ACCESS), no single causative environmental agent has been identified. Family clustering and differences in racial incidence of sarcoidosis support an inherited susceptibility to sarcoidosis. Siblings of patients with sarcoidosis have about a...
Topics
- Black or African American
- Butyrophilins
- Chromosomes, Human, Pair 5
- Chromosomes, Human, Pair 6
- Genetic Linkage
- Genetic Predisposition to Disease
- Genetics, Population
- Granuloma
- Granuloma, Respiratory Tract
- HLA Antigens
- Humans