Article
Correlation of the genotypes for N-acetyltransferases 1 and 2 with double bladder and prostate cancers in a case-comparison study.
Anticancer research - 1 Jan 2000
Wang Ching Y, Jones Richard F, Debiec-Rychter Maria, Soos Gyorgyike, Haas Gabriel P
Abstract excerpt
BACKGROUND: The arylamine N-acetyltransferases play a major role in the metabolic activation of carcinogenic amines that are present in cigarette smoke and a variety of other exogenous sources. The objective of this study was to determine the association of rapid or slow arylamine N-acetyltransferase (NAT) genotypes with smoking history and the risk for developing both bladder and prostate cancer. PATIENTS AND...
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