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Article

Phenothiazines and Thioxanthenes Inhibit Multidrug Efflux Pump Activity in <i>Staphylococcus aureus</i>

23 Jan 2003

Abstract excerpt

Efflux-related multidrug resistance (MDR) is a significant means by which bacteria can evade the effects of selected antimicrobial agents. Genome sequencing data suggest that Staphylococcus aureus may possess numerous chromosomally encoded MDR efflux pumps, most of which have not been characterized. Inhibition of these pumps, which may restore clinically relevant activity of antimicrobial agents that are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12543683
DOI: 10.1128/aac.47.2.719-726.2003

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