Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thymoquinone’ potent impairment of multidrug-resistant Staphylococcus aureus NorA efflux pump activity

17 Jul 2024

Abstract excerpt

The drug efflux pump is a crucial mechanism implicated in resistance to multiple antimicrobials. Thymoquinone (TQ) has evidently demonstrated multiple activities, antibacterial being the most effective. Knowledge about TQ activity against multidrug-resistant Staphylococcus aureus is very scarce. Therefore, the present study was conducted to investigate TQ resistance modulation in ciprofloxacin (CIP) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioactive Compounds and Antitumor Agents
Share to Pharmacological Effects of Natural Compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39013998
DOI: 10.1038/s41598-024-65991-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thymoquinone’ potent impairment of multidrug-resistant Staphylococcus aureus NorA efflux pump activityPMID 39013998Read ↗

In vitro profiling of antimethicillin-resistant Staphylococcus aureus activity of thymoquinone against selected type and clinical strainsSemantic proximity Read ↗

Jatrorrhizine suppresses the antimicrobial resistance of methicillin‑resistant Staphylococcus aureusSemantic proximity Read ↗

NorA, Tet(K), MepA, and MsrA Efflux Pumps in Staphylococcus aureus, their Inhibitors and 1,8-Naphthyridine SulfonamidesSemantic proximity Read ↗

<i>In Vitro</i> and <i>In Vivo</i> Investigations into the Potential of Quinazoline and Quinoline Derivatives as NorA Efflux Pump Inhibitors Against Resistant <i>Staphylococcus aureus</i> StrainsSemantic proximity Read ↗

Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps.Semantic proximity Read ↗

In vitro antimicrobial activity and resistance mechanisms of the new generation tetracycline agents, eravacycline, omadacycline, and tigecycline against clinical Staphylococcus aureus isolatesSemantic proximity Read ↗

Evolution from a natural flavones nucleus to obtain 2-(4-Propoxyphenyl)quinoline derivatives as potent inhibitors of the S. aureus NorA efflux pump.Semantic proximity Read ↗

Systematic Analysis of Efflux Pump-Mediated Antiseptic Resistance in Staphylococcus aureus Suggests a Need for Greater Antiseptic Stewardship.Semantic proximity Read ↗

Investigation of Phage Activity in Combination with Thyme Oil Against Methicillin-Resistant Staphylococcus aureus (MRSA)Semantic proximity Read ↗

Investigation of Phage Activity in Combination with Thyme Oil Against Methicillin-Resistant Staphylococcus aureus (MRSA)Semantic proximity Read ↗

Efflux-mediated Multidrug Resistance in Critical Gram-negative Bacteria and Natural Efflux Pump InhibitorsSemantic proximity Read ↗

Synergy of clavine alkaloid 'chanoclavine' with tetracycline against multi-drug-resistant E. coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.