Article
Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps.
Bioorganic chemistry - 1 Oct 2017
Tintino Saulo R, Morais-Tintino Cícera D, Campina Fábia F, Costa Maria do S, Menezes Irwin R A, de Matos Yedda Maria L S, Calixto-Júnior João T, Pereira Pedro S, Siqueira-Junior José P, Leal-Balbino Teresa C, Coutinho Henrique D M, Balbino Valdir Q
Abstract excerpt
The widespread use of antibiotics created selective pressure for the emergence of strains that would persist despite antibiotic toxicity. The bacterial resistance mechanisms are several, with efflux pumps being one of the main ones. These pumps are membrane proteins with the function of removing antibiotics from the cell cytoplasm. Due to this importance, the aim of this work was to evaluate the inhibitory effect...
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