Article
Functional properties of the sex-hormone-binding globulin (SHBG)-like domain of the anticoagulant protein S.
European journal of biochemistry - 1 Feb 2003
Saposnik Béatrice, Borgel Delphine, Aiach Martine, Gandrille Sophie
Abstract excerpt
Protein S (PS) possesses a sex-hormone-binding globulin (SHBG)-like domain in place of the serine-protease domain found in other vitamin K-dependent plasma proteins. This SHBG-like domain is able to bind a complement fraction, C4b-binding protein (C4b-BP). To establish whether the PS SHBG-like domain can fold normally in the absence of other domains, and to obtain information on the specific functions of this...
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