Article
Fidelity in planar cell polarity signalling.
Nature - 30 Jan 2003
Ma Dali, Yang Chung-hui, McNeill Helen, Simon Michael A, Axelrod Jeffrey D
Abstract excerpt
The polarity of Drosophila wing hairs displays remarkable fidelity. Each of the approximately 30,000 wing epithelial cells constructs an actin-rich prehair that protrudes from its distal vertex and points distally. The distal location and orientation of the hairs is virtually error free, thus forming a nearly perfect parallel array. This process is controlled by the planar cell polarity signalling pathway. Here...
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