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Article

Colonial morphology of Burkholderia cepacia complex genomovar III: implications in exopolysaccharide production, pilus expression, and persistence in the mouse.

Infection and immunity - 1 Feb 2003

Chung Jacqueline W, Altman Eleonora, Beveridge Terry J, Speert David P

Abstract excerpt

The purpose of this study was to determine the role of colonial morphology of Burkholderia cepacia complex (BCC) organisms in pathogenicity in a mouse model of pulmonary infection. BCC strain C1394 was rapidly cleared by leukopenic mice after intranasal challenge, whereas a spontaneous variant (C1394mp2) that was indistinguishable from the parent strain by genetic typing persisted in the lungs and differed in...

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Identifiers

PMID: 12540572
DOI: 10.1128/IAI.71.2.904-909.2003
PMCID: PMC145372

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