Article
Two polymorphisms in the fracalkine receptor CX3CR1 are not associated with peripheral arterial disease.
Atherosclerosis - 1 Feb 2003
Gugl Alexander, Renner Wilfried, Seinost Gerald, Brodmann Marianne, Pabst Edmund, Wascher Thomas C, Paulweber Bernhard, Iglseder Bernhard, Pilger Ernst
Abstract excerpt
OBJECTIVE: CX(3)CR1 is a novel chemokine receptor located on monocytes. Recently, two polymorphisms were linked to coronary artery disease (CAD), V249I and T280M. Carriers of at least one I-allele or one M-allele were found less frequently among patients with CAD compared to controls. The aim of the present study was to investigate the influence of these polymorphisms on the development of peripheral arterial...
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