Article
Odontoblast-specific expression of cre recombinase successfully deletes gene segments flanked by loxP sites in mouse teeth.
Genesis (New York, N.Y. : 2000) - 1 Feb 2003
Sreenath T L, Cho A, Thyagarajan T, Kulkarni A B
Abstract excerpt
Embryonic or neonatal lethality of mice with targeted disruption of critical genes preclude them from further characterization of specific roles of these genes during postnatal development and aging. In order to study the molecular roles of such genes in teeth, we generated transgenic mouse lines expressing bacteriophage Cre recombinase under the control of the mouse dentin sialophosphoprotein (dspp) gene...
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