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Functional crosstalk between hOgg1 and the helicase domain of Cockayne syndrome group B protein.

DNA repair - 3 Nov 2002

Tuo Jingsheng, Chen Catheryne, Zeng Xianmin, Christiansen Mette, Bohr Vilhelm A

Abstract excerpt

We have previously reported that the Cockayne syndrome group B gene product (CSB) contributes to base excision repair (BER) of 8-hydroxyguanine (8-OH-Gua) and the importance of motifs V and VI of the putative helicase domains of CSB in BER of 8-OH-Gua. To further elucidate the function of CSB in BER, we investigated its role in the pathway involving human 8-OH-Gua glycosylase/apurinic lyase (hOgg1). Depletion of...

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Identifiers

PMID: 12531019
DOI: 10.1016/s1568-7864(02)00116-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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