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Article

SF1 polymorphisms in the mouse and steroidogenic potential.

Endocrine research - 1 Nov 2002

Schimmer Bernard P, Cordova Martha, Tsao Jennivine, Frigeri Claudia

Abstract excerpt

ACTH-resistance in four mutant derivatives of a mouse adrenocortical tumor cell line results from a defect that reduces the activity of steroidogenic factor-1 (SF1) thereby preventing expression of the ACTH receptor and other SF1-dependent genes. The SF1 genes from these mutants contain a sequence difference that changes an Ala to Ser at codon 172. Steroidogenic factor-1(S172) represents a polymorphism rather...

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Identifiers

PMID: 12530657
DOI: 10.1081/erc-120016832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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