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Article

High prevalence of the EBER variant EB-8m in endemic nasopharyngeal carcinomas.

PloS one - 1 Jan 2015

Shen Zhi-chao, Luo Bing, Chen Jian-ning, Chao Yan, Shao Chun-kui, Liu Qian-qian, Wang Yun

Abstract excerpt

Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) are the most highly expressed transcripts in all EBV-associated tumors and are involved in both lymphoid and epithelioid carcinogenesis. Our previous study on Chinese isolates from non-endemic area of nasopharyngeal carcinoma (NPC) identified new EBER variants (EB-8m and EB-10m) which were less common but relatively more frequent in NPC cases than healthy...

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Identifiers

PMID: 25807550
DOI: 10.1371/journal.pone.0121420
PMCID: PMC4373760

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